In Indigenous communities Kambô is used to gain strength, boost immunity, maintain or regain health, and heal disease. It's often applied before hunting to increase strength, health, stamina and vision. They also use it for rainforest specific issues, such as malaria, yellow fever and snake and spider bites. Immediate and short term effects include enhanced mood, alertness, clarity, focus, energy and increased resistance to stress and tiredness.

As it is one of the strongest natural anti-inflammatory, antibiotic, antimicrobial and anaesthetic substances found on the planet, there are endless physical benefits to Kambô. It helps to strengthen the immune system, start the detoxification process of the liver, kidneys and intestines.


Kambô contains numerous peptides that provoke the destruction of pathogenic microorganisms and strengthen the immune system through the body’s production of antibodies against the secretion. These peptides are showing great power in the treatment of Parkinsons and Alzheimer Disease, AIDS, cancer, depression, addictions, PTSD, hormonal imbalances and many other diseases. 


During the 1980's, Italian scientist and Nobel prize nominee, 'Vittorio Erspamer of the University of Rome wrote that this secretion contains a ‘fantastic chemical cocktail with potential medical applications, unequaled by any other amphibian’.


Among the several dozen peptides found in Kambô, up to 7% are bio-active. They bind with receptor sites situated in the brain, triggering chemical reactions in the human body. So far, researchers have found nine bioactive peptides that have a potent effect on the gastrointestinal muscles, gastric and pancreatic secretions, blood circulation and on the stimulation of the adrenal cortex and pituitary gland.


Phyllomedusin strongly affects intestines, bowels and contributes to deep purging.

Phyllokinin and Phyllomedusin are potent vessel dilators, increasing the permeability of the blood-brain barrier. This facilitates access to the brain of these two, as well as the other active peptides.


Caerulein and Sauvagine cause a fall in blood pressure accompanied by tachycardia. They stimulate the adrenal cortex and the pituitary gland, contributing to heightened sensory perception and increased stamina. Both of these peptides have a strong analgesic effect, enhance endurance, increase physical strength and in general, enhance the capacity to face pain and stressful situations. They possess medical potential as digestive aids, and have demonstrated analgesic effects for those with renal colic pain due to peripheral vascular insufficiency and cancer pain.


Dermorphin and Deltorphin are potent opioid peptides 4000 times stronger than morphine and 40 times stronger than endogenic b-endorphines. In the 1990’s, a new peptide, Adenoregulin, was discovered by John Daly’s team at the National Institute of Health in the USA.


Adenoregulin works in the human body through the adenosine receptors, a fundamental component in all human cell fuel. These receptors can offer a target for treating depression, stroke seizures and cognitive loss ailments such as Alzheimer’s disease. Scientific research on the peptides of Kambô are opening up new perspectives on how the human brain works. The properties of Kambô peptides cover a wide range of potential medical uses: treatment of brain diseases such as Alzheimer’s and Parkinson’s, depression, migraines, blood circulation problems, vascular insufficiency, organ diseases, skin and eyes issues, fertility problems in women and men, AIDS, hepatitis, cancer, etc. Other interesting medicinal properties of this secretion are its anti-inflammatory effects, its capacity to destroy microbes and viruses and heal infections. Due to the presence of these nine peptides, Kambô is one of the strongest natural antibiotics and anaesthetics found in the world and one of the strongest, natural ways to empower our immune system.